A large body of evidence has been collected indicating that the addition of individual amino acids to the diet in special proportions improves the immune status, thereby reducing morbidity and mortality.
LOW-PROTEIN DIET IMPAIRS IMMUNE FUNCTION
Unhealthy diet, malnutrition, in particular, insufficient intake of protein from food, and infections are the main vital problems in human life. This global topic led to the emergence of a new scientific discipline, food immunology, which combines dietetics and immunological research to determine the role of nutrients in the metabolism and the functioning of the immune system at the molecular, cellular, tissue and systemic levels of the human body. Recent studies have shown that protein deficiency in food compromises the effectiveness of both innate and acquired human immunity. The determination of the degree of participation of individual amino acids in immune responses has helped in developing effective strategies for improving health and preventing infectious diseases.
AMINO ACIDS ARE THE PRIMARY DEFENDERS AGAINST DISEASES
Amino acids affect all parts of the immune system, these are actually different parts of the immune system that not only constantly protect your body from invaders (viruses, fungi, bacteria), but also slow the aging processes under the influence of adverse factors such as ultraviolet radiation and pollutants containing free radicals from the environment. When any of these enemies tries to destroy the defense line of the immune system, it starts the destruction of complex protein structures of cells in your body and disturbs the metabolism. This disturbance manifests itself in the form of diarrhea, allergy, runny nose, cough, vulnerability to herpes viruses, hepatitis, as well as in the form of colitis, ulcers, tumors, premature aging and other disorders. We will show you how amino acid mixtures help to successfully resist diseases by strengthening immunity.
The immune system protects you from a variety of pathogens and consists of innate (natural, nonspecific) and acquired (adaptive, specific) immunity.
These two systems are closely interrelated.
The innate immune system responds quickly to an infectious invasion, but its main deficiencies include the lack of specificity and "immune memory." When an infection cannot be defeated by the innate immunity within a short period of time, the acquired immune system is activated to effectively destroy infectious agents.
In the acquired immune system, each lymphocyte has on its surface receptors for a single antigen, thereby providing highly specific immune responses.
This system becomes effective within a few days after the initial contact with the infection, because it has immunological memory.
Both immune systems strongly depend on the adequate intake of amino acids for the synthesis of their own peptides and polypeptides, as well as other molecules of enormous biological significance. These substances include nitric oxide (NO), superoxide, hydrogen peroxide, histamine, glutathione and anthranilic acid. Amino acids affect immune responses either directly or indirectly through their metabolites.
While the immune system is vital to health, it can be dysfunctional under certain conditions, resulting in the development of diseases, such as insulin-dependent diabetes mellitus (type 1), rheumatoid arthritis and asthma.
T CELL PROTECTION
As far as the immune system is concerned, the main property of amino acid mixtures is that amino acids–being constituents of proteins–are involved in the function of endocrine system at all its levels. Parts of this system are the thyroid gland, pancreas, sex glands, adrenal glands, etc.
Different glands produce different hormones. For example, the adrenal glands produce adrenaline, which accelerates metabolic processes in the body and the reaction "fight or flight." The thyroid hormone thyroxine is responsible for food metabolism and recovery. However, among the glands the main role in the immune response is played by the thymus gland. Of several amino acids and cofactors, this gland produces hormone thymosin. Under its influence, the spleen, together with the lymph nodes, begins to produce T lymphocytes, which protect us from pathogenic agents. T lymphocytes are a kind of security service in the body, they circulate in the blood, penetrate into each capillary and are present in all parts of our huge organism tracing enemies. When lymphocytes detect a pathogenic "enemy" microorganism, they immediately give an alarm signal. The first ones to come for help are amine derivatives called lymphokines. They can be called our own natural medicines of our body, and one of them is well-known interferon. Lymphokines begin to attack microorganisms and toxic substances, tearing them apart, after which they no longer pose such a great danger and the body can get rid of them. If the invader is large, then a stronger unit, called macrophages, enters the battle. Literally translated, this word means "large eaters," and macrophages fully warrant the name. They "engulf" the invaders and destroy them within themselves using enzymes. Amino acids improve capillary blood flow, thereby helping lymphocytes to quickly reach the site of penetration of the "enemy."
WHAT IS ANTIBODY?
T cell protection is only one part of the defense. The other part is called B cell antibodies or immunoglobulin response. B cells are produced in the bone marrow from chains of amino acids. We have five groups of antibodies, each of which reacts to various types of threats: bacteria, viruses, toxins, etc.
How do they work? They attach to foreign invaders and inactivate them.
But when they cannot cope with this task, macrophages come to help again and finish the job.
T cells and B cells often work together. Let's see how this happens. In the T cell group, there are helper cells and suppressor cells. When T cells detect an "enemy," they produce additional cells–helpers, which send a command to increase the production of B cell antibodies. On the other hand, suppressors minimize the speed of antibody production when they are not needed. The ratio between helpers and suppressors is maintained by substances called prostaglandins, which are synthesized during the metabolic process from linoleic acid that is part of fatty acids. And, just as with any metabolic process, the synthesis of prostaglandins from linoleic acid is impossible without amino acids.
IMMUNOACTIVE GROUP OF AMINO ACIDS
Arginine, valine, leucine, isoleucine, glutamine, glycine, histidine, methionine, tryptophan and cysteine are prominent representatives of the amino acids of this group. But when the balance is not observed, when the mechanism of antagonism between amino acids, the nature of the disease, and individual characteristics of the person are ignored, the result can be negative. All this must be taken into account when taking amino acids.
The IMS amino acid strategy is based on deep knowledge of the biochemistry and physiology of amino acids, their role in immune reactions. Amino acids are effective in improving the health and prevention of infectious diseases in humans. There are amino acids that are involved in the reactions of immunity directly in the form of individual molecules rather than as part of proteins. Such amino acids include: threonine, valine, tryptophan, aspartic and glutamic acid, serine, alanine, cystine and gamma-aminobutyric acid (GABA). These amino acids form a group of immunoactive amino acids.
Aspartic and glutamic acids accelerate the transformation in the bone marrow of the progenitors of immune cells, T lymphocytes, into mature cells. Along with tryptophan, they stimulate thymus-dependent immunity.
Glutamine is synthesized and stored in muscles, if necessary, muscle proteins break down and glutamine enters the bloodstream where it is used to build immune cells. This explains the muscle pains in many infections, because the body takes glutamine from the muscles to promptly fend off the enemy. Under normal conditions, the body maintains a balance between the intake and synthesis of glutamine in the muscles, between its excretion and the synthesis of immune cells.
The production of antibodies is stimulated by gamma-aminobutyric acid (GABA).
Arginine stimulates phagocytosis–devouring by protective cells, phagocytes, of foreign proteins, including bacteria and viruses.
Methionine, arginine and valine are burned in the cell bioreactor, providing cellular immunity with energy.
Methionine and cysteine have a pronounced antioxidant effect, protecting the body cells from free radicals formed during the neutralization of biologically alien aggressors. They activate lymphocytes, stimulate cellular and humoral immunity.
Serotonin and its precursor, the amino acid tryptophan, regulate immunity in intestinal cells, providing the overall body resistance.
THE ROLE OF THE GASTROINTESTINAL TRACT IN IMMUNITY
The first line of your immune defense against billions of pathogens that besiege your body is the gastrointestinal system: your stomach and intestines. The secreted acids and enzymes not only digest food in there, but also protect against fermentation, decay and the formation of dangerous toxins. Along with other parts of our body, the gastrointestinal system is a fragile mechanism, balancing between incredible efficacy and chronic diseases. For example, the large intestine contains a huge amount of potentially dangerous bacteria and yeast strains responsible for digesting food. Only our body has enzymes responsible for controlling these microorganisms, which, if given a chance, will begin to multiply uncontrollably, leading to disorders and diseases. Which is what often happens, unfortunately, because of the huge consumption of refined food. Fresh fruits and vegetables contain substances that help to limit the growth of pathogenic bacteria in the intestines and provide nutrition for beneficial microorganisms. Consumption of refined food destroys many of these substances, creating favorable conditions for the uncontrolled proliferation of pathogenic microflora to a dangerous level. In the presence of a large number of yeast strains, food begins to ferment in the intestine. The resulting alcohol is absorbed into the blood, to which the body reacts by lowering the sugar level, a person experiences fatigue and lethargy. At the same time, the protective intestinal lining begins to lose its integrity, and the under-digested proteins easily penetrate through it and are absorbed into the blood. But our body can only take amino acids, so it perceives these protein molecules as viruses and bacteria and starts to fight them, that's how food allergy develops.
Let's move on. Oxygen in the intestines, which is so necessary for digestion, is absorbed by bacteria, and rotting begins in the intestine with the formation of poisonous substances that are absorbed into the blood, poisoning the entire body. Spreading through the body with blood stream, these toxic substances displace the actual neurotransmitters and, being inert substances, block the transfer of information between cells and disrupt the metabolism. One of the most dangerous forms of fungal strains is candida albicans. The number of people with this candidiasis is growing steadily, and this pathogenic flora causes a wide range of diseases from arthritis to hypertension.
What can you do to prevent this unpleasant situation? If the dangerous reproduction of fungal flora occurs partly because of a lack of enzymes, the best way to protect yourself is to increase the level of enzymes. You need to eat raw, organic food. But if you already have digestive problems, you need a special set of wholesome food that will also help you to recover, especially in combination with special amino acid mixtures. Overall, about fifteen thousand enzymes are synthesized in our pancreas from amino acid precursors. Providing the pancreas with these precursors in the required amount from special mixtures, you help to increase the level of digestive enzymes, thereby reducing the amount of undigested food available to bacteria.
PROTECTION FROM FREE RADICALS
Enzymes formed from amino acids help to protect your body from damage by free radicals. Free radicals are unstable molecules often found in contaminated air and water. Unlike other molecules containing paired electrons, free radicals have an unpaired electron. Searching for a pair for the free electron, they often capture an electron from other, balanced molecules of healthy tissues, tearing protein structures of the skin and organs to pieces, causing ailments and diseases. Heavy metals and ultraviolet radiation are one of the main causes of free radical damage to the body. Amino acids protect the body's tissues from free radicals, such as heavy metals, by binding them and leaving healthy tissues untouched.
IMMUNITY AND SPECIAL AMINO ACID COMBINATIONS
Every cell, every hormone and every organ of your immune system consists of proteins. Therefore, the intake of amino acid mixtures, even if you are not sick, will provide metabolic support in the functioning and effectiveness of the immune system. Although individual amino acids are used with incredible efficiency to eliminate individual disorders, these special mixtures have proven themselves in practice as real defenders against diseases.
As you already know, in order to work successfully, they need a well-functioning circulatory system (arterial, venous, lymphatic). The circulatory system for them is not only roads and paths, but also a system for delivering building materials to the organs they are produced by–thymus, spleen, and lymph nodes.
People who suffer from cardiovascular diseases, obesity, those who smoke, drink alcohol, have impaired circulatory system, which leads to more frequent or serious illnesses.
We recommend to combine the intake of amino acids with a program of physical activity
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